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I had been using Quinine Sulphate capsules for many years for severe leg cramps at night. I did not take a capsule every day but only when I had been on my feet all day and sometimes after a long day of golf or walking in heeled shoes. My doctor felt I was responsible enough to give me a bottle of 100 pills. This often lasted me well into two years or so. I have had leg cramps once again often since I was unable to purchase these capsules any longer. If they are again available I will be really content to once again be able to rid myself of severe cramps at least most of the time if I think of the circumstances of my day.

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Last year I have traveled to Madagascar. It is the biggest island in the Indian Ocean and the biggest island in the whole world. The flora and fauna are astonishing there, as well as the range of different bacteria and infections one can catch there. Before the trip I have taken Quinine to protect me from malaria as it is a very nasty disease to catch. I started on Quinine two days before the departure and continued for several days after I came back. I believe it's due to Quinine that I have not contracted malaria, neither have I had any side effects connected with taking the medication. It is very important that such vital drugs that help prevent life-threatening diseases do not create major difficulties for people who have no other way out but taking them.

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This necessitated a sporogonic cycle (the time interval during which the parasite developed in the mosquito).

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However, data as recent as 2011 indicate that the majority of quinine use in this country continues to be related to leg cramps and muscle pain, and continue to be reported.

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Chemists later determined that the active ingredient in this healing bark was quinine, and it was used around the world wherever mosquitoes carried the disease.

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First Doctors told us it was due to the quinine treatment, that when quinine come out from the blood he would recover vision.

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British and Italian schools of malariology over priority, but Ross received the 1902 Nobel Prize for Physiology or Medicine for "his work on malaria, by which he has shown how it enters the organism and thereby has laid the foundation for successful research on this disease and methods of combating it".

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Quinine, then, was an ingredient central to not only the gin and tonic, but also the growth of European imperialism.

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Bhattarai A, Ali AS, Kachur SP, Mårtensson A, Abbas AK, Khatib R, Al-Mafazy AW, Ramsan M, Rotllant G, Gerstenmaier JF, Molteni F, Abdulla S, Montgomery SM, Kaneko A, Björkman A: Impact of artemisinin-based combination therapy and insecticide-treated nets on malaria burden in Zanzibar.

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